Ergodic pumping: A mechanism to drive biomolecular conformation changes
نویسندگان
چکیده
منابع مشابه
Ergodic Pumping: a mechanism to drive biomolecular conformation changes
We propose that a significant contribution to the power stroke of myosin and similar conformation changes in other biomolecules is the pressure of a single molecule (e.g. a phosphate ion) expanding a trap, a mechanism we call “ergodic pumping”. We demonstrate the principle with a toy computer model and discuss the mathematics governing the evolution of slow degrees of freedom in large Hamiltoni...
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ژورنال
عنوان ژورنال: Physica D: Nonlinear Phenomena
سال: 2006
ISSN: 0167-2789
DOI: 10.1016/j.physd.2006.02.006